N-Carbamylglutamic Acid

Nhamba yeCAS: 1188-38-1

Molecular Formula: C6H10N2O5

Molecular uremu: 190.15  

EINECS Nha.: 601-569-3

1. Chikafu cheMhuka uye Zvekudya Zvinowedzerwa (1) Kukurudzira Endogenous Arginine Synthesis Mechanism of Action: NCG inoshanda sechinhu chakakosha chepakati (imwe substrate) munzira yearginine synthesis. Nekumisikidza carbamoyl phosphate synthetase I (CPS I), inosimudzira urea kutenderera uye arginine synthesis, inosimudzira zvakanyanya endo native arginine mazinga-kunyanya mumhuka diki (semuenzaniso, nguruve, mhuru, makwayana) ine underdeveloped arginine synthesis kugona. Migumisiro: Kuvandudzwa Kwekukura Kwekuita: Kuwedzera kuwedzera kwezuva nezuva kurema (~ 5% -15%) uye kuderedzwa kwekudya-ku-kuwana chiyero (~ 3% -8%).
   
   

Kuderedza Diarrhea: Inosimbisa intestinal mucosal barrier function uye kudzivirirwa, kuderedza manyoka munguruve dzakarumurwa. Kuwedzeredzwa Kwekubereka Kuita: Kunovandudza goho remukaka wekudyara uye mhando, kuwedzera huwandu hwekupona kwenguruve dzinoyamwisa.

2. Kutsiviwa kweDirect Arginine Supplementation Advantages: Arginine inodhura uye inokonzeresa kushatiswa nematumbu, nepo NCG yakagadzikana mumakemikari uye inonyatso kushandurwa kuita arginine, ichideredza mutengo wekudya. Yakanakira mhuka diki (semuenzaniso, nguruve dzichangozvarwa) uye mhuka dziri pasi pekunetsekana (semuenzaniso, kushushikana kwekupisa, kupora kwechirwere).

Human Medical Applications (1) Kurapa kweUrea Cycle Disorders Zviratidzo : NCG, seanalog yemaitiro eN-acetylglutamic acid (NAG), inoshandisa CPS I kubatsira ammonia metabolism. Inoshandiswa kurapa urea cycle kusagadzikana senge N-acetylglutamate synthase (NAGS) kushomeka. Administration: Oral kana intravenous, kuderedza mazinga eammonia eropa. (2) Zvokudya Zvokudya uye Metabolic Support Applications : Inovandudza mapuroteni metabolism mukutambudzika, postoperative, kana varwere vanorwara zvakanyanya. Inotsigira kurapwa kweammonia metabolism kusagadzikana kunokonzerwa nekusashanda kwechiropa.

3. Chikafu Chipfuwo Mabasa: Inosimudzira hutano hwematumbo muimbwa nekatsi, kuderedza mapuroteni metabolism nekuda kwekusasimba kugaya. Inowedzera kusadzivirirwa uye kukura kwekukura mumhuka dzinovaraidza (semuenzaniso, puppies, kittens). 4. Zvekurima uye Tsvagiridzo Dzinoshandiswa Kutsvagisa: Inoongorora basa rearginine metabolism mukudzora kukura kwemhuka, kuberekana, uye kusadzivirirwa. Inoshanda sechishandiso chemushonga kuenzanisira kana kupindira muzvirwere zvine chekuita neurea (semuenzaniso, mumbeva, zebrafish).

Chiyero Chinokurudzirwa (Mienzaniso Yekudya kweMhuka) Chikamu cheMhuka Chinokurudzirwa Chiyero (% mukudya) Zvinangwa Zvikuru

Chengetedzo Kuchengeteka: Nyatsotevedzera zviyero zvinokurudzirwa kumhuka; kuwandisa madosi kunogona kukonzera ammonia metabolic mutoro. Kushandiswa kwevanhu kunoda kutarisirwa kwechiremba.

Kugarisana: Synergizes nemavhitamini (semuenzaniso, B6) uye zvicherwa (semuenzaniso, zinc) kuwedzera metabolic mhedzisiro. ,

Kuchengeta: Chengeta munzvimbo inotonhorera, yakaoma (<25°C), yakachengetedzwa kubva kuchiedza uye mwando.

Sherufu hupenyu: 24 mwedzi.

Kutakura: 25kg / chigubhu