N-Carbamylglutamic Acid

Inombolo yeCAS: 1188-38-1

Ifomula yemolekyuli: C6H10N2O5

Ubunzima beMolekyuli: 190.15  

Inombolo ye-EINECS: 601-569-3

1. Isondlo sezilwanyana kunye nezongezo zokutya (1) Ukukhuthaza i-Arginine Synthesis ye-Endogenous Mechanism of Action: I-NCG isebenza njengeyona nto ibalulekileyo ephakathi (enye i-substrate) kwindlela ye-arginine synthesis. Ngokuvula i-carbamoyl phosphate synthetase I (CPS I), iphucula umjikelo we-urea kunye ne-arginine synthesis, inyusa kakhulu amanqanaba e-arginine e-endogenous-ingakumbi kwizilwanyana ezincinci (umz., amantshontsho eehagu, amathole, amatakane) ezinomthamo ongaphuhlisiyo we-arginine synthesis. Iziphumo: UkuPhuculwa kokuSebenza okuPhuculweyo: Ukunyuswa kobunzima bemihla ngemihla (~ 5% -15%) kunye nokunciphisa umlinganiselo wesondlo ukuya kwinzuzo (~3% -8%).
   
   

Uhudo oluncitshisiweyo: Lomeleza umsebenzi wokuthintelwa kwamathumbu emathunjini kunye nokungakhuseleki, ukwehlisa izinga lorhudo kumantshontsho ehagu elunyulwe. Ukomelezwa kokuNzala kweNzala: Kuphucula isivuno sobisi lwemazi kunye nomgangatho, ukonyusa amazinga okuphila kwamantshontsho ancancayo.

2. Ukutshintshwa kwe-Arginine Supplementation eNgcebelekayo: I-Arginine ineendleko kwaye ijwayele ukuthotywa yi-gut microbes, ngelixa i-NCG izinzile ngokwekhemikhali kwaye iguqulelwe ngokufanelekileyo kwi-arginine, inciphisa iindleko zokutya. Ilungele izilwanyana ezincinci (umzekelo, amantshontsho eehagu asandul' ukuzalwa) kunye nezilwanyana eziphantsi koxinzelelo (umzekelo, uxinzelelo lobushushu, ukuchacha kwezifo).

Izicelo zezoNyango zoLuntu (1) Unyango lwe-Urea Cycle Disorders Izibonakaliso : I-NCG, njenge-analog yesakhiwo se-N-acetylglutamic acid (NAG), isebenze i-CPS I ukunceda i-ammonia metabolism. Isetyenziselwa ukuphatha ukuphazamiseka komjikelo we-urea njenge-N-acetylglutamate synthase (NAGS) ukusilela. Ulawulo : Ngomlomo okanye nge-intravenous, ukunciphisa amanqanaba e-ammonia yegazi. (2) Izicelo zenkxaso yezondlo kunye ne-Metabolic : Ukuphucula i-protein metabolism kwi-trauma, postoperative, okanye izigulane ezigula kakhulu. Ixhasa unyango lwe-ammonia metabolism ukuphazamiseka okubangelwa ukungasebenzi kakuhle kwesibindi.

3. Ukutya kwezilwanyana zasekhaya: Yongeza impilo yamathumbu ezinjeni nasezikatini, ukunciphisa imiba yeprotheyini yemetabolism ngenxa yobuthathaka bokugaya. Yongeza ukhuseleko kunye namazinga okukhula kwizilwanyana zasekhaya (umzekelo, iinjana, amantshontsho). 4. EzoLimo kunye noPhando oluSetyenziswayo: Iphanda indima ye-arginine metabolism ekulawuleni ukukhula kwezilwanyana, ukuzala, kunye nokungakhuseleki. Isebenza njengesixhobo sokwenza imodeli okanye ukungenelela kwizifo ezinxulumene nomjikelo we-urea (umzekelo, kwiimpuku, i-zebrafish).

Umthamo oCetyisiweyo (Imizekelo yokutya kwezilwanyana) Udidi lweZilwanyana oluCetyisiweyo Umthamo (% kwisondlo) Iinjongo eziphambili

Ukhuseleko: Landela ngokungqongqo iidosi ezicetyiswayo zezilwanyana; Iidosi ezigqithisileyo zinokukhokelela kumthwalo we-ammonia metabolic. Ukusetyenziswa komntu kufuna uhlolo lwezonyango.

Ukuhambelana: Isebenzisana neevithamini (umzekelo, i-B6) kunye neeminerali (umzekelo, i-zinc) ukuphucula iziphumo ze-metabolic. ...

Ugcino: Gcina kwindawo epholileyo, eyomileyo (<25°C), ekhuselwe ekukhanyeni nasekufumameni.

Ubomi beshelufu: iinyanga ezingama-24.

Ukupakisha: 25kg / igubu