S-(Carboxymethyl)-L-cysteine

Khoom Taw Qhia

CAS Nr .: 2387-59-9

Molecular Formula: C₅H₉NO₄S

Molecular Luj: 179.19

EINECS NO.: 219-193-9

Lub luag hauj lwm thiab kev ua tau zoo ntawm S-(Carboxymethyl)-L-cysteine hauv Animal Healthcov

S-(Carboxymethyl)-L-cysteine ​​(tseem hu ua Carbocysteine) yog ib qho derivative ntawm cysteine ​​thiab belongs rau mucoregulator thiab antioxidant class, zoo ib yam li acetylcysteine ​​(NAC). Txawm li cas los xij, nws cov qauv tshuaj thiab cov txheej txheem ntawm kev ua haujlwm txawv heev. Hauv qab no yog cov ntsiab lus ntawm nws lub luag haujlwm thiab kev tshawb fawb txog kev noj qab haus huv ntawm tsiaj:

covI. Core Mechanisms and Effectscov

cov1. Kev tiv thaiv mucolytic thiab ua pacov

• covKev ua: Tswj cov kab mob hauv cov hlab ntsha thiab txo cov hnoos qeev viscosity los ntawm kev hloov cov enzyme kev ua cuam tshuam rau cov hnoos qeev (tsis zoo li NAC, uas ncaj qha zom cov hnoos qeev ntawm disulfide bond cleavage).

• covHom phiaj:

covTsiaj (dog / miv): Mob ntsws ntsws, mob ntsws nrog cov hnoos qeev tuab.

covTsiaj txhu (kua / swine): Kab mob kab mob los yog kab mob ua pa (xws li swine enzootic pneumonia).

cov2. Antioxidant thiab Anti-inflammatory teebmeemcov

• covMechanism: Txhim kho intracellular glutathione (GSH) qib thiab suppresses pro-inflammatory cytokines (piv txwv li, IL-8, TNF-α), alleviating airway o.

• covDaim ntawv thov:

• covNqaij qaib: Mitigates oxidative kev puas tsuaj los ntawm ammonia los yog hmoov av raug.

• covAquaculture: Tiv thaiv oxidative kev nyuaj siab nyob rau hauv high-density ua liaj ua teb ib puag ncig.

cov3. Immunomodulationcov

• Txhim khu kev tiv thaiv mucosal thiab tuaj yeem txhim kho cov tshuaj tiv thaiv zoo (piv txwv li, hauv cov kab mob porcine respiratory syndrome).

cov

III. Kev tshawb nrhiav thiab kev siv hauv Tsiaj Noj Qab Haus Huvcov

cov1. Ua liaj ua tebcov

• covCov ntaub ntawv sim: Ntxiv S-(Carboxymethyl)-L-cysteine ​​(50–100 mg/kg) rau broiler pub txo cov kab mob ua pa los ntawm ammonia raug thiab txhim kho qhov hnyav nce los ntawm 5-8%.

• covKev tswj hwm: Los ntawm cov dej haus los yog pub rau 5-7 hnub.

cov2. Tsiaj (Dog/Cas)cov

• covKev Tswj Kab Mob Hlwb: Kev noj qhov ncauj ntawm 10-15 mg / kg ob zaug ib hnub rau 2 lub lis piam txo qhov hnoos ntau zaus.

cov3. Aquaculturecov

• covKev Tiv Thaiv Kev Nyuaj Siab: Pub supplementation (200–300 mg/kg) mitigates oxidative puas thaum thauj los yog dej tsis zoo, txhim kho cov ciaj sia taus.

covIV. Cov kev ceev fajcov

1. covDosage Control:

Kev noj tshuaj ntau dhau tuaj yeem ua rau mob raws plab (tshwj xeeb tshaj yog nyob rau hauv cov nqaij qaib).

covCov tshuaj sib cuam tshuam:

• Tsis txhob siv cov tshuaj acidic (piv txwv li, vitamin C) lossis tshuaj tua kab mob (xws li tetracyclines).

covTxoj Cai Ua Raws Cai:

• covTuam Tshoj: Yuav tsum ua raws li Veterinary Drug Administration Regulationsthiab lub sijhawm tshem tawm.

• covEU: Tseem tsis tau pom zoo raws li cov tshuaj kws kho tsiaj; ua raws li cov cai hauv zos.

covV. Cov Lus Qhia Txog Kev Tshawb Fawbcov

• covAntiviral Adjuvant: Cov kev tshawb fawb hauv vitro qhia tias inhibition of avian influenza virus (H9N2) replication; xav tau ntxiv validation.

• covKev Noj Qab Nyob Zoo: Txhim kho antioxidant muaj peev xwm ntawm cov phev los yog oocytes hauv cov tsiaj yug me nyuam (kev sim theem).

covCov ntsiab luscov

S-(Carboxymethyl)-L-cysteine ​​feem ntau yog siv rau tsiaj noj qab haus huv rauKev tswj kab mob ua pa ntevthiabtiv thaiv antioxidant txhawb. Nws qhov kev ua me me thiab kev nyab xeeb siab profile ua rau nws tsim nyog rau kev siv mus ntev, txawm tias nws qhov pib qeeb qeeb txwv kev siv hluav taws xob hauv cov mob hnyav. Thaum ua ke nrog NAC, ob tus neeg sawv cev sib koom ua ke hauv kev daws teeb meem kev noj qab haus huv thiab mob hnyav. Kev siv tswv yim yuav tsum xav txog hom kev xav tau tshwj xeeb, theem kab mob, thiab cov txheej txheem tswj hwm.

Rau cov ncauj lus kom ntxaws txog kev siv tshuaj los yog cov txheej txheem tshuaj kho mob, xav nug!