S- (Carboxymethyl) -L-cysteine

Ọja Ifihan

CAS No.: 2387-59-9

Fọọmu Molecular:C₅H₉NO₄S

Òṣuwọn Molecular:179.19

EINECS RẸ: 219-193-9

Ipa ati ipa ti S- (Carboxymethyl) -L-cysteine ni Animal Healtho

S- (Carboxymethyl) -L-cysteine ​​​​(ti a tun mọ ni Carbocysteine ​​​​) jẹ itọsẹ ti cysteine ​​ati pe o jẹ ti mucoregulator ati kilasi antioxidant, gẹgẹbi acetylcysteine ​​​​(NAC). Sibẹsibẹ, ilana kemikali rẹ ati siseto iṣe ṣe yatọ ni pataki. Ni isalẹ jẹ awotẹlẹ ti awọn ipa rẹ ati ilọsiwaju iwadii ni ilera ẹranko:

oI. Core Mechanisms ati awọn ipao

o1. Mucolytic ati Idaabobo Ẹmio

• oIṣe‌: Ṣe atunṣe yomijade mucus oju-ofurufu ati dinku iki sputum nipa ṣiṣatunṣe iṣẹ ṣiṣe enzymu ti o nii ṣe pẹlu iṣelọpọ mucus (kii ṣe NAC, eyiti o fọ mucus taara nipasẹ cleavage mnu disulfide).

• oÀkọlé Eya:

oAwọn ohun ọsin (awọn aja/ologbo)‌: bronchitis onibaje, pneumonia pẹlu sputum ti o nipọn.

oẸran-ọsin (malu/elede)‌: Kokoro tabi gbogun ti atẹgun atẹgun (fun apẹẹrẹ, pneumonia enzootic ẹlẹdẹ).

o2. Antioxidant ati Awọn ipa-iredodoo

• oIlana‌: Ṣe ilọsiwaju awọn ipele intracellular glutathione (GSH) ati ki o dinku awọn cytokines pro-iredodo (fun apẹẹrẹ, IL-8, TNF-a), imukuro iredodo ọna atẹgun.

• oAwọn ohun elo:

• oAdie‌: Mitigates oxidative bibajẹ lati amonia tabi ekuru ifihan.

• oAquaculture‌: Ṣe aabo fun aapọn oxidative ni awọn agbegbe ogbin iwuwo giga.

o3. Immunomodulationo

• Ṣe okunkun ajesara mucosal ati pe o le jẹki imunadoko ajesara (fun apẹẹrẹ, ni aarun aarun atẹgun ti porcine).

o

III. Iwadi ati Awọn ohun elo ni Ilera Erankoo

o1. Adie Ogbino

• oData Idanwo‌: Fifi S- (Carboxymethyl) -L-cysteine ​​​​(50-100 mg / kg) si ifunni broiler dinku awọn ọgbẹ atẹgun ti o fa nipasẹ ifihan amonia ati ki o mu ilọsiwaju iwuwo nipasẹ 5-8%.

• oIsakoso: Nipasẹ omi mimu tabi ifunni fun awọn ọjọ 5-7.

o2. Ohun ọsin (Ajá/Ológbò)o

• oOnibaje Bronchitis Management‌: Dosing oral ni 10-15 mg/kg lẹmeji ojoojumo fun ọsẹ 2 ni pataki dinku igbohunsafẹfẹ Ikọaláìdúró.

o3. Aquacultureo

• oIdaabobo Wahala‌: Ifunni ifunni (200-300 mg / kg) n ṣe ipalara ibajẹ oxidative lakoko gbigbe tabi awọn ipo omi ti ko dara, imudarasi awọn oṣuwọn iwalaaye.

oIV. Àwọn ìṣọ́rao

1. oIṣakoso doseji:

Aṣeju iwọn lilo le fa igbuuru kekere (paapaa ni adie).

oOògùn Awọn ibaraẹnisọrọ:

• Yago fun lilo nigbakanna pẹlu awọn aṣoju ekikan (fun apẹẹrẹ, Vitamin C) tabi awọn egboogi (fun apẹẹrẹ, tetracyclines).

oIbamu Ilana:

• oChina: Gbọdọ ni ibamu pẹlu Ti ogbo Oògùn Isakoso Ilanaati yiyọ akoko.

• oEU‌: Ko tii fọwọsi bi oogun ti ogbo akọkọ; tẹle awọn ilana agbegbe.

oV. Awọn itọnisọna Iwadi ti o pọjuo

• oAntiviral Adjuvant‌: Awọn ẹkọ in vitro daba idinamọ ti aarun ayọkẹlẹ aarun ayọkẹlẹ avian (H9N2) ẹda; siwaju afọwọsi ti nilo.

• oIlera ibisi‌: Ṣe ilọsiwaju agbara antioxidant ti àtọ tabi awọn oocytes ninu awọn ẹranko ibisi (ipele idanwo).

oLakotano

S- (Carboxymethyl) -L-cysteine ​​​​jẹ lilo akọkọ ni ilera ẹranko fun ‌iṣakoso arun atẹgun onibajeatiatilẹyin antioxidant gbèndéke. Iṣe ìwọnba ati profaili aabo giga jẹ ki o dara fun lilo igba pipẹ, botilẹjẹpe ibẹrẹ ibẹrẹ rẹ losokepupo awọn iwulo ni awọn ipo nla. Nigbati a ba ni idapo pẹlu NAC, awọn aṣoju meji naa ṣe iranlowo fun ara wọn ni titọkasi mejeeji onibaje ati awọn italaya ilera nla. Awọn ohun elo adaṣe gbọdọ gbero awọn iwulo-ẹya kan pato, awọn ipele arun, ati awọn itọsọna ilana.

Fun alaye awọn itọkasi idanwo tabi awọn ilana iwọn lilo ti adani, lero ọfẹ lati beere!