S-(Carboxymethyl) -L-cysteine

Chiyambi cha Zamalonda

Nambala ya CAS: 2387-59-9

Kapangidwe ka Molecular: C₅H₉NO₄S

Kulemera kwa Maselo: 179.19

EINECS NO.: 219-193-9

Udindo ndi Kuchita bwino kwa S-(Carboxymethyl) -L-cysteine mu Animal Healthpa

S-(Carboxymethyl) -L-cysteine ​​​​(yomwe imadziwikanso kuti Carbocysteine) ndi yochokera ku cysteine ​​​​ndipo ndi ya mucoregulator ndi antioxidant class, yofanana ndi acetylcysteine ​​(NAC). Komabe, kapangidwe kake ka mankhwala ndi kachitidwe kake zimasiyana kwambiri. Pansipa pali chithunzithunzi cha ntchito zake komanso momwe kafukufukuyu akuyendera paumoyo wa nyama:

paI. Njira Zazikulu ndi Zotsatira zakepa

pa1. Chitetezo cha Mucolytic ndi kupumapa

• paZochita: Imawongolera katulutsidwe ka ntchofu ndipo imachepetsa kukhuthala kwa sputum posintha zochita za ma enzyme okhudzana ndi kupanga ntchofu (mosiyana ndi NAC, yomwe imaphwanya mwachindunji ntchofu kudzera pa disulfide bond cleavage).

• paMitundu Yandanda:

paZiweto (agalu / amphaka): Matenda a bronchitis, chibayo chokhala ndi sputum wandiweyani.

paNg'ombe (ng'ombe / nkhumba): Matenda a bakiteriya kapena mavairasi (monga chibayo cha nkhumba cha enzootic).

pa2. Antioxidant ndi Anti-inflammatory Effectspa

• paNjira: Imakulitsa ma intracellular glutathione (GSH) ndikupondereza ma cytokines oyambitsa kutupa (mwachitsanzo, IL-8, TNF-α), kuchepetsa kutupa kwapanjira.

• paMapulogalamu:

• paNkhuku: Imachepetsa kuwonongeka kwa okosijeni kuchokera ku ammonia kapena kukhudzana ndi fumbi.

• paZamoyo zam'madzi: Imateteza kupsinjika kwa okosijeni m'malo olimidwa kwambiri.

pa3. Immunomodulationpa

• Imalimbitsa chitetezo cham'mimba ndipo imatha kupititsa patsogolo mphamvu ya katemera (mwachitsanzo, porcine kupuma kwa matenda).

pa

III. Research and Applications in Animal Healthpa

pa1. Kuweta Nkhukupa

• paData Data: Kuonjezera S-(Carboxymethyl)-L-cysteine ​​(50–100 mg/kg) ku chakudya cha broiler kumachepetsa zotupa za kupuma zomwe zimayambitsidwa ndi ammonia ndikuwonjezera kulemera ndi 5-8%.

• paUlamuliro: Kudzera madzi akumwa kapena chakudya kwa masiku 5-7.

pa2. Ziweto (Agalu/ Amphaka)pa

• paChithandizo cha Chronic Bronchitis: Kumwa pakamwa pa 10-15 mg/kg kawiri pa tsiku kwa masabata a 2 kumachepetsa kwambiri chifuwa.

pa3. Kulima m'madzipa

• paKutetezedwa Kupsinjika: Chakudya chowonjezera (200-300 mg / kg) chimachepetsa kuwonongeka kwa okosijeni panthawi yoyendetsa kapena madzi osakhala bwino, kupititsa patsogolo kupulumuka.

paIV. Kusamalitsapa

1. paKuwongolera Mlingo:

Mankhwala osokoneza bongo angayambitse kutsekula m'mimba pang'ono (makamaka nkhuku).

paKugwiritsa Ntchito Mankhwala:

• Pewani kugwiritsa ntchito nthawi imodzi ndi asidi (monga vitamini C) kapena maantibayotiki (mwachitsanzo, tetracyclines).

paKutsata Malamulo:

• paChina: Muyenera kutsatira Malamulo a Veterinary Drug Administrationndi nthawi zochotsa.

• paEU: Osavomerezedwa ngati mankhwala odziwika bwino azinyama; kutsatira malamulo akumaloko.

paV. Njira Zofufuza Zomwe Zingathekepa

• paAntiviral Adjuvant: Kafukufuku wa in vitro akuwonetsa kuletsa kachirombo ka avian influenza virus (H9N2); kutsimikizira kwina kofunikira.

• paUchembere wabwino: Imawonjezera mphamvu ya antioxidant ya umuna kapena oocyte pakuweta nyama (gawo loyesera).

paChidulepa

S-(Carboxymethyl) -L-cysteine ​​​​amagwiritsidwa ntchito makamaka paumoyo wa nyama kwa ‌kasamalidwe ka matenda opumirandichithandizo cha antioxidant. Kuchita kwake pang'onopang'ono komanso chitetezo chapamwamba kumapangitsa kuti ikhale yoyenera kugwiritsidwa ntchito kwa nthawi yayitali, ngakhale kuyamba kwake pang'onopang'ono kumalepheretsa kugwiritsidwa ntchito pazovuta kwambiri. Pophatikizidwa ndi NAC, othandizira awiriwa amathandizirana pothana ndi zovuta zathanzi komanso zovuta. Zomwe zimagwiritsidwa ntchito ziyenera kuganizira zosowa zamtundu wamtundu, magawo a matenda, ndi malangizo owongolera.

Kuti mumve zambiri zoyeserera kapena ma protocol osinthidwa makonda, omasuka kufunsa!